004.942
53.05
617.735

біооб’єкт
біосигнал
відгук
синхронізація
когерентна фільтрація
достовірність
ефективність
bioobject
biosignal
response
synchronization
coherent filtration
confidence
efficiency

Запропоновано спосіб синхронізації однорідних біосигналів в їх ансамблі. Основною метою синхронізації є забезпечення автоматизованого якісного когерентного оцінювання біосигналу. Розроблено, апробовано та представлено алгоритми тестування, синхронізації та когерентної фільтрації усередненням. Результати використано для автоматизації інформаційно-аналітичних біомедичних систем та застосовано в активних експериментах, коли відгук біооб’єкта носить нестаціонарний стохастичний характер.
For controlling and diagnosing of functional state, for correction functions of biological object the method of electrophysiological active research of this object often use. In particularly the use of low level light intensity (LLLI) for stimulation of biological object (information influence on biological object) is effective enough. The tendencies to reduce of light intensity is caused by necessity as comfortable conditions for biological object so and (in concordance with Weber-Fechner's law) increasing informativeness of response of that biological object. However, the ratio of response power to the noise power (RRN) is decreasing strongly after that. Decreasing intensity of stimulation is causing increasing of the initial (latent) part of the response of bio-object. In addition, the length of latent parts responses are stochastic. Therefore, there is a need of statistical estimation ensemble of these responses with aim to improve RRN. The standard method estimating of the response is the averaging of the responses, estimating the moment of first order of probability distribution function of values the responses. Estimating statistical characteristics of the response of bioobject on to LLLI stimulation using statistical processing of ensemble of the responses is the problem. Using interactive synchronization procedures, and synchronization automation by using perfusing blood or by heart rhythm greatly complicates both hardware and software. In this paper are given results of researching and using special measures for taking in attention the nonstationarity of ensemble. Ensuring the samples coherence in ensemble for improving accuracy and the confidence level of the sample estimate is discussed. Methods automate synchronization of biosignal's samples in their an ensemble are presented. Are developed algorithms of synchronization, coherent filtration and statistical tests, these are approbated and presented. The main aim of the researches directed for providing conditions coherent filtering of biosignals, has been achieved. Results are used for automation of information-analytics biomedical systems active explorations of bioobject when its response is stochastic.

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